Effect of Medium-chain Triacylglycerols on Anti-obesity Effect of Fucoxanthin

Effect of Medium-chain Triacylglycerols on Anti-obesity Effect of Fucoxanthin
(Received May 2, 2007)
(Accepted August 21, 2007)
Hayato Maeda, Masashi Hosokawa, Tokutake Sashima, Katsura Funayama and
Kazuo Miyashita
Journal of Oleo Science

Abstract: Dietary effects of medium-chain triacylglycerols (MCT) and fucoxanthin (Fc) on abdominal fat weight were determined using KK-Ay obese mouse. Experimental diet contained MCT(0.9%), Fc (0.1%), or MCT (0.9%) +Fc (0.1%). The abdominal fat weight of mice fed with Fc was significantly lower than that of mice fed with MCT. Uncoupling protein 1 (UCP1), a key molecule for metabolic thermogenesis, was clearly expressed in the white adipose tissue (WAT) of mice fed Fc, but little expression in that of the mice fed MCT. The anti-obesity effect of Fc was increased by mixing Fc with MCT. This increase would be due to the increase in the absorption rate of Fc by MCT.

Key words: fucoxanthin, obesity, medium-chain triacylglycerol

To cite this article:
Hayato Maeda, Masashi Hosokawa, Tokutake Sashima, Katsura Funayama and Kazuo Miyashita, “Effect of Medium-chain Triacylglycerols on Anti-obesity Effect of Fucoxanthin”, J. Oleo Sci., Vol. 56, 615-621 (2007) .

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Copyright (c) 2007 by Japan Oil Chemists' Society